Methylsulfonylnitrobenzoates, a New Class of Irreversible Inhibitors of the Interaction of the Thyroid Hormone Receptor and Its Obligate Coactivators That Functionally Antagonizes Thyroid Hormone

Thyroid hormone receptors (TRs) are members of the nuclear hormone receptor (NR) superfamily and regulate development, growth, and metabolism. Upon binding thyroid hormone, TR undergoes a conformational change that allows the release of corepressors and the recruitment of coactivators, which in turn...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hwang, Jong Yeon, Huang, Wenwei, Arnold, Leggy A., Huang, Ruili, Attia, Ramy R., Connelly, Michele, Wichterman, Jennifer, Zhu, Fangyi, Augustinaite, Indre, Austin, Christopher P., Inglese, James, Johnson, Ronald L., Guy, R. Kiplin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069392/
https://ncbi.nlm.nih.gov/pubmed/21321127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200436
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados