A Quantitative High Throughput Screen Identifies Novel Inhibitors of the Interaction of Thyroid Receptor β with a Peptide of Steroid Receptor Coactivator 2

The thyroid hormone receptors (TR) are members of the nuclear hormone receptor (NHR) superfamily that regulate development, growth, and metabolism. Upon ligand binding, TR releases bound corepressors and recruits coactivators to modulate target gene expression. Steroid Receptor Coactivator 2 (SRC2)...

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Main Authors: Johnson, Ronald L., Hwang, Jong Yeon, Arnold, Leggy A., Huang, Ruili, Wichterman, Jennifer, Augustinaite, Indre, Austin, Christopher P., Inglese, James, Guy, R. Kiplin, Huang, Wenwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162318/
https://ncbi.nlm.nih.gov/pubmed/21482722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111402199
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