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Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor

The crucial role of cell signaling in hemostasis is clearly established by the action of the downstream coagulation protease thrombin that cleaves platelet-expressed G-protein-coupled protease activated receptors (PARs). Certain PARs are cleaved by the upstream coagulation proteases factor Xa (Xa) a...

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Bibliografske podrobnosti
Main Authors: Riewald, Matthias, Ruf, Wolfram
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC35412/
https://ncbi.nlm.nih.gov/pubmed/11438726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141126698
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