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Disulfide isomerization switches tissue factor from coagulation to cell signaling
Cell-surface tissue factor (TF) binds the serine protease factor VIIa to activate coagulation or, alternatively, to trigger signaling through the G protein-coupled, protease-activated receptor 2 (PAR2) relevant to inflammation and angiogenesis. Here we demonstrate that TF·VIIa-mediated coagulation a...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1599891/ https://ncbi.nlm.nih.gov/pubmed/16959886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606411103 |
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