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Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor

The crucial role of cell signaling in hemostasis is clearly established by the action of the downstream coagulation protease thrombin that cleaves platelet-expressed G-protein-coupled protease activated receptors (PARs). Certain PARs are cleaved by the upstream coagulation proteases factor Xa (Xa) a...

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Detalhes bibliográficos
Main Authors: Riewald, Matthias, Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35412/
https://ncbi.nlm.nih.gov/pubmed/11438726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141126698
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