Comprehensive Behavioral Phenotyping of Ts65Dn Mouse Model of Down Syndrome: Activation of β(1)-Adrenergic Receptor by Xamoterol as a Potential Cognitive Enhancer

Down Syndrome (DS) is the most prevalent form of mental retardation caused by genetic abnormalities in humans. This has been successfully modeled in mice to generate the Ts65Dn mouse, a genetic model of DS. This transgenic mouse model shares a number of physical and functional abnormalities with peo...

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Main Authors: Faizi, Mehrdad, Bader, Patrick L., Tun, Christine, Encarnacion, Angelo, Kleschevnikov, Alexander, Belichenko, Pavel, Saw, Nay, Priestley, Matthew, Tsien, Richard W, Mobley, William C, Shamloo, Mehrdad
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539757/
https://ncbi.nlm.nih.gov/pubmed/21527343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.011
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