Deficits in Cognition and Synaptic Plasticity in a Mouse Model of Down Syndrome Ameliorated by GABA(B) Receptor Antagonists

Cognitive impairment in Down syndrome (DS) is characterized by deficient learning and memory. Mouse genetic models of DS exhibit impaired cognition in hippocampally mediated behavioral tasks and reduced synaptic plasticity of hippocampal pathways. Enhanced efficiency of GABAergic neurotransmission w...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kleschevnikov, Alexander M., Belichenko, Pavel V., Faizi, Mehrdad, Jacobs, Lucia F., Htun, Khin, Shamloo, Mehrdad, Mobley, William C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411326/
https://ncbi.nlm.nih.gov/pubmed/22764230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1673-12.2012
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller