Hippocampal Long-Term Potentiation Suppressed by Increased Inhibition in the Ts65Dn Mouse, a Genetic Model of Down Syndrome

Although many genetic disorders are characterized by cognitive failure during development, there is little insight into the neurobiological basis for the abnormalities. Down syndrome (DS), a disorder caused by the presence of three copies of chromosome 21 (trisomy 21), is characterized by impairment...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kleschevnikov, Alexander M., Belichenko, Pavel V., Villar, Angela J., Epstein, Charles J., Malenka, Robert C., Mobley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729789/
https://ncbi.nlm.nih.gov/pubmed/15371516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1766-04.2004
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