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Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome
GABAergic dysfunction is implicated in hippocampal deficits of the Ts65Dn mouse model of Down syndrome (DS). Since Ts65Dn mice overexpress G-protein coupled inward-rectifying potassium (GIRK2) containing channels, we sought to evaluate whether increased GABAergic function disrupts the functioning of...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123861/ https://ncbi.nlm.nih.gov/pubmed/22178330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.11.033 |
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