Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome

GABAergic dysfunction is implicated in hippocampal deficits of the Ts65Dn mouse model of Down syndrome (DS). Since Ts65Dn mice overexpress G-protein coupled inward-rectifying potassium (GIRK2) containing channels, we sought to evaluate whether increased GABAergic function disrupts the functioning of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Best, Tyler K., Cramer, Nathan P., Chakrabarti, Lina, Haydar, Tarik F., Galdzicki, Zygmunt
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123861/
https://ncbi.nlm.nih.gov/pubmed/22178330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.11.033
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