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Longitudinal measures of cognition in the Ts65Dn mouse: refining windows and defining modalities for therapeutic intervention in Down syndrome

Mouse models have provided insights into adult changes in learning and memory in Down syndrome, but an in-depth assessment of how these abnormalities develop over time has never been conducted. To address this shortcoming, we conducted a longitudinal behavioral study from birth until late adulthood...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Olmos-Serrano, J. Luis, Tyler, William A., Cabral, Howard J., Haydar, Tarik F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716476/
https://ncbi.nlm.nih.gov/pubmed/26854932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.02.005
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