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Defects in Embryonic Neurogenesis and Initial Synapse Formation in the Forebrain of the Ts65Dn Mouse Model of Down Syndrome

Trisomy 21, one of the most prevalent congenital birth defects, results in a constellation of phenotypes collectively termed Down syndrome (DS). Mental retardation and motor and sensory deficits are among the many debilitating symptoms of DS. Alterations in brain growth and synaptic development are...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Chakrabarti, Lina, Galdzicki, Zygmunt, Haydar, Tarik F.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673208/
https://ncbi.nlm.nih.gov/pubmed/17959791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3406-07.2007
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