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Defects in Embryonic Neurogenesis and Initial Synapse Formation in the Forebrain of the Ts65Dn Mouse Model of Down Syndrome

Trisomy 21, one of the most prevalent congenital birth defects, results in a constellation of phenotypes collectively termed Down syndrome (DS). Mental retardation and motor and sensory deficits are among the many debilitating symptoms of DS. Alterations in brain growth and synaptic development are...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chakrabarti, Lina, Galdzicki, Zygmunt, Haydar, Tarik F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673208/
https://ncbi.nlm.nih.gov/pubmed/17959791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3406-07.2007
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