Autophagy Plays an Essential Role in Mediating Regression of Hypertrophy during Unloading of the Heart

Autophagy is a bulk degradation mechanism for cytosolic proteins and organelles. The heart undergoes hypertrophy in response to mechanical load but hypertrophy can regress upon unloading. We hypothesize that autophagy plays an important role in mediating regression of cardiac hypertrophy during unlo...

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Hlavní autoři: Hariharan, Nirmala, Ikeda, Yoshiyuki, Hong, Chull, Alcendor, Ralph R., Usui, Soichiro, Gao, Shumin, Maejima, Yasuhiro, Sadoshima, Junichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538681/
https://ncbi.nlm.nih.gov/pubmed/23308102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051632
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