Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure-Overload-Induced Mitochondrial Dysfunction and Heart Failure

BACKGROUND: Mitochondrial autophagy is an important mediator of mitochondrial quality control in cardiomyocytes. The occurrence of mitochondrial autophagy and its significance during cardiac hypertrophy are not well understood. METHODS AND RESULTS: Mice were subjected to transverse aortic constricti...

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Vydáno v:Circulation
Hlavní autoři: Shirakabe, Akihiro, Zhai, Peiyong, Ikeda, Yoshiyuki, Saito, Toshiro, Maejima, Yasuhiro, Hsu, Chiao-Po, Nomura, Masatoshi, Egashira, Kensuke, Levine, Beth, Sadoshima, Junichi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811679/
https://ncbi.nlm.nih.gov/pubmed/26915633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.020502
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