Autophagy Plays an Essential Role in Mediating Regression of Hypertrophy during Unloading of the Heart

Autophagy is a bulk degradation mechanism for cytosolic proteins and organelles. The heart undergoes hypertrophy in response to mechanical load but hypertrophy can regress upon unloading. We hypothesize that autophagy plays an important role in mediating regression of cardiac hypertrophy during unlo...

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Detalhes bibliográficos
Main Authors: Hariharan, Nirmala, Ikeda, Yoshiyuki, Hong, Chull, Alcendor, Ralph R., Usui, Soichiro, Gao, Shumin, Maejima, Yasuhiro, Sadoshima, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538681/
https://ncbi.nlm.nih.gov/pubmed/23308102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051632
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