uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK

We hypothesized that urokinase plasminogen activator (uPA) contributes to age-dependent early hyperemia after fluid percussion brain injury (FPI) by activating extracellular signal-related kinase (ERK) mitogen-activated protein kinase (MAPK), leading to histopathologic changes in the underlying cort...

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Detalhes bibliográficos
Main Authors: Armstead, William M, Cines, Douglas B, Bdeir, Khalil H, Bdeir, Yasmina, Stein, Sherman C, Higazi, Abd Al-Roof
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538352/
https://ncbi.nlm.nih.gov/pubmed/19050721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.142
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