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tPA Contributes To Impairment of ATP and Ca Sensitive K Channel Mediated Cerebrovasodilation After Hypoxia/Ischemia Through Upregulation of ERK MAPK
The sole FDA approved treatment for acute stroke is tissue type plasminogen activator (tPA). However, tPA potentiates impairment of pial artery dilation in response to hypotension after hypoxia/ischemia (H/I) in pigs. ATP and Ca sensitive K channels (Katp and Kca) are important regulators of cerebro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038175/ https://ncbi.nlm.nih.gov/pubmed/21182829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.12.052 |
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