IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

Parasitic helminths are a major cause of chronic human disease, affecting more than 3 billion people worldwide. Host protection against most parasitic helminths relies upon Type 2 cytokine production, but the mechanisms that regulate interleukin (IL) 4 and 13 production from CD4(+) T helper 2 cells...

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Detalhes bibliográficos
Main Authors: Hung, Li-Yin, Lewkowich, Ian P., Dawson, Lucas A., Downey, Jordan, Yang, Yanfen, Smith, Dirk E., Herbert, De'Broski R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538196/
https://ncbi.nlm.nih.gov/pubmed/23248269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206587110
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