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Myeloid-restricted AMPKα1 promotes host immunity and protects against IL12/23p40-dependent lung injury during hookworm infection

How the metabolic demand of parasitism affects immune-mediated resistance is poorly understood. Immunity against parasitic helminthes requires M2 cells and interleukin-13 (IL-13), secreted by CD4(+) T(H)2 and group 2 innate lymphoid cells (ILC2), but whether certain metabolic enzymes control disease...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Nieves, Wildaliz, Hung, Li-Yin, Oniskey, Taylor K., Boon, Louis, Foretz, Marc, Viollet, Benoit, Herbert, De'Broski R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875814/
https://ncbi.nlm.nih.gov/pubmed/27183598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502218
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