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Myeloid-restricted AMPKα1 promotes host immunity and protects against IL12/23p40-dependent lung injury during hookworm infection
How the metabolic demand of parasitism affects immune-mediated resistance is poorly understood. Immunity against parasitic helminthes requires M2 cells and interleukin-13 (IL-13), secreted by CD4(+) T(H)2 and group 2 innate lymphoid cells (ILC2), but whether certain metabolic enzymes control disease...
Enregistré dans:
| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875814/ https://ncbi.nlm.nih.gov/pubmed/27183598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502218 |
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