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AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

AMPK is a serine/threonine kinase that regulates energy homeostasis and metabolic stress in eukaryotes. Previous work from our laboratory, as well as by others, has provided evidence that AMPKα1 acts as a negative regulator of TLR-induced inflammatory function. Herein, we demonstrate that AMPKα1-def...

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Detalhes bibliográficos
Main Authors: Carroll, Kelly Casey, Viollet, Benoit, Suttles, Jill
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828606/
https://ncbi.nlm.nih.gov/pubmed/23883517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0313157
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