TGF-β–Responsive Myeloid Cells Suppress Type 2 Immunity and Emphysematous Pathology after Hookworm Infection

Transforming growth factor β (TGF-β) regulates inflammation, immunosuppression, and wound-healing cascades, but it remains unclear whether any of these functions involve regulation of myeloid cell function. The present study demonstrates that selective deletion of TGF-βRII expression in myeloid phag...

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Hlavní autoři: Heitmann, Lisa, Rani, Reena, Dawson, Lucas, Perkins, Charles, Yang, Yanfen, Downey, Jordan, Hölscher, Christoph, Herbert, De'Broski R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432431/
https://ncbi.nlm.nih.gov/pubmed/22901754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.05.032
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