Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

The molecular mechanisms that drive mucosal T helper type 2 (T(H)2) responses against parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that TFF2 (trefoil factor 2), an epithelial cell–derived repair molecule, is needed for the control of lung injury caused by t...

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Auteurs principaux: Wills-Karp, Marsha, Rani, Reena, Dienger, Krista, Lewkowich, Ian, Fox, James G., Perkins, Charles, Lewis, Lauren, Finkelman, Fred D., Smith, Dirk E., Bryce, Paul J., Kurt-Jones, Evelyn A., Wang, Timothy C., Sivaprasad, Umasundari, Hershey, Gurjit K., Herbert, De’Broski R.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302229/
https://ncbi.nlm.nih.gov/pubmed/22329990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110079
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