Myeloid-Derived IL-33 Limits the Severity of Dextran Sulfate Sodium–Induced Colitis

IL-33 is an IL-1 family cytokine that signals through its cognate receptor, ST2, to regulate inflammation. Whether IL-33 serves a pathogenic or protective role during inflammatory bowel disease is controversial. Herein, two different strains of cell-specific conditionally deficient mice were used to...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Hung, Li-Yin, Pastore, Christopher F., Douglas, Bonnie, Herbert, De’Broski R.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2021
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863133/
https://ncbi.nlm.nih.gov/pubmed/33245913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.11.004
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