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Production of Gastrointestinal Tumors in Mice by Modulating Latent Transforming Growth Factor Beta 1 Activation
Transforming growth factor-β (TGF-β) and its signaling pathways are important mediators in the suppression of cancers of the gastrointestinal (GI) tract. TGF-β is released from cells in a latent complex consisting of TGF-β, the TGF-β propeptide (LAP) and a latent TGF-β binding protein (LTBP). We pre...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537847/ https://ncbi.nlm.nih.gov/pubmed/23117884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3141 |
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