Perturbation of transforming growth factor (TGF)-ß1 association with latent TGF-β binding protein yields inflammation and tumors

Transforming growth factor-β (TGF-β) activity is controlled at many levels including the conversion of the latent secreted form to its active state. TGF-β is often released as part of an inactive tripartite complex consisting of TGF-β, the TGF-β propeptide, and a molecule of latent TGF-β binding pro...

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Detalhes bibliográficos
Main Authors: Yoshinaga, Keiji, Obata, Hiroto, Jurukovski, Vladimir, Mazzieri, Roberta, Chen, Yan, Zilberberg, Lior, Huso, David, Melamed, Jonathan, Prijatelj, Petra, Todorovic, Vesna, Dabovic, Branka, Rifkin, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596235/
https://ncbi.nlm.nih.gov/pubmed/19022904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805411105
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