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Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion

BACKGROUND: Endothelin, via endothelin A receptors (ETA), exerts multiple pathologic effects that contribute to disease pathogenesis throughout the body. ETA antagonists ameliorate many experimental diseases and have been extensively utilized in clinical trials. The utility of ETA blockers has been...

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書誌詳細
主要な著者: Stuart, Deborah, Rees, Sara, Woodward, Stephanie K, Koesters, Robert, Strait, Kevin A, Kohan, Donald E
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537641/
https://ncbi.nlm.nih.gov/pubmed/23217151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-13-166
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