Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion

BACKGROUND: Endothelin, via endothelin A receptors (ETA), exerts multiple pathologic effects that contribute to disease pathogenesis throughout the body. ETA antagonists ameliorate many experimental diseases and have been extensively utilized in clinical trials. The utility of ETA blockers has been...

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Main Authors: Stuart, Deborah, Rees, Sara, Woodward, Stephanie K, Koesters, Robert, Strait, Kevin A, Kohan, Donald E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537641/
https://ncbi.nlm.nih.gov/pubmed/23217151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-13-166
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