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Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion

BACKGROUND: Endothelin, via endothelin A receptors (ETA), exerts multiple pathologic effects that contribute to disease pathogenesis throughout the body. ETA antagonists ameliorate many experimental diseases and have been extensively utilized in clinical trials. The utility of ETA blockers has been...

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Autors principals: Stuart, Deborah, Rees, Sara, Woodward, Stephanie K, Koesters, Robert, Strait, Kevin A, Kohan, Donald E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537641/
https://ncbi.nlm.nih.gov/pubmed/23217151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-13-166
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