Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia

The persistence of minimal residual disease (MRD) during therapy is the strongest adverse prognostic factor in acute lymphoblastic leukemia (ALL). We developed a high-throughput sequencing method that universally amplifies antigen-receptor gene segments and identifies all clonal gene rearrangements...

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Bibliografske podrobnosti
Main Authors: Faham, Malek, Zheng, Jianbiao, Moorhead, Martin, Carlton, Victoria E. H., Stow, Patricia, Coustan-Smith, Elaine, Pui, Ching-Hon, Campana, Dario
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2012
Teme:
Clinical Trials and Observations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537310/
https://ncbi.nlm.nih.gov/pubmed/23074282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-444042
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