Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia

Minimal residual disease (MRD) at the end of remission-induction therapy predicts relapse in acute lymphoblastic leukemia (ALL). We examined the clinical significance of levels below the usual threshold value for MRD positivity (0.01%) in 455 children with B-lineage ALL, using polymerase chain react...

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Detalhes bibliográficos
Main Authors: Stow, Patricia, Key, Laura, Chen, Xiaohua, Pan, Qiulu, Neale, Geoffrey A., Coustan-Smith, Elaine, Mullighan, Charles G., Zhou, Yinmei, Pui, Ching-Hon, Campana, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890183/
https://ncbi.nlm.nih.gov/pubmed/20304809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-253435
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