Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia

The persistence of minimal residual disease (MRD) during therapy is the strongest adverse prognostic factor in acute lymphoblastic leukemia (ALL). We developed a high-throughput sequencing method that universally amplifies antigen-receptor gene segments and identifies all clonal gene rearrangements...

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Detalhes bibliográficos
Main Authors: Faham, Malek, Zheng, Jianbiao, Moorhead, Martin, Carlton, Victoria E. H., Stow, Patricia, Coustan-Smith, Elaine, Pui, Ching-Hon, Campana, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537310/
https://ncbi.nlm.nih.gov/pubmed/23074282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-444042
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