Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia

The persistence of minimal residual disease (MRD) during therapy is the strongest adverse prognostic factor in acute lymphoblastic leukemia (ALL). We developed a high-throughput sequencing method that universally amplifies antigen-receptor gene segments and identifies all clonal gene rearrangements...

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Библиографические подробности
Главные авторы: Faham, Malek, Zheng, Jianbiao, Moorhead, Martin, Carlton, Victoria E. H., Stow, Patricia, Coustan-Smith, Elaine, Pui, Ching-Hon, Campana, Dario
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2012
Предметы:
Clinical Trials and Observations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537310/
https://ncbi.nlm.nih.gov/pubmed/23074282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-444042
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