Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration

Although phosphatidylinositol 5-phosphate (PtdIns5P) is present in many cell types and its biogenesis is increased by diverse stimuli, its precise cellular function remains elusive. Here we show that PtdIns5P levels increase when cells are stimulated to move and we find PtdIns5P to promote cell migr...

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Detaylı Bibliyografya
Asıl Yazarlar: Oppelt, Angela, Lobert, Viola H, Haglund, Kaisa, Mackey, Ashley M, Rameh, Lucia E, Liestøl, Knut, Oliver Schink, Kay, Marie Pedersen, Nina, Wenzel, Eva M, Haugsten, Ellen M, Brech, Andreas, Erik Rusten, Tor, Stenmark, Harald, Wesche, Jørgen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: European Molecular Biology Organization 2013
Konular:
Scientific Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537138/
https://ncbi.nlm.nih.gov/pubmed/23154468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.183
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