Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration

Although phosphatidylinositol 5-phosphate (PtdIns5P) is present in many cell types and its biogenesis is increased by diverse stimuli, its precise cellular function remains elusive. Here we show that PtdIns5P levels increase when cells are stimulated to move and we find PtdIns5P to promote cell migr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Oppelt, Angela, Lobert, Viola H, Haglund, Kaisa, Mackey, Ashley M, Rameh, Lucia E, Liestøl, Knut, Oliver Schink, Kay, Marie Pedersen, Nina, Wenzel, Eva M, Haugsten, Ellen M, Brech, Andreas, Erik Rusten, Tor, Stenmark, Harald, Wesche, Jørgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
Schlagworte:
Scientific Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537138/
https://ncbi.nlm.nih.gov/pubmed/23154468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.183
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge