Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration

Although phosphatidylinositol 5-phosphate (PtdIns5P) is present in many cell types and its biogenesis is increased by diverse stimuli, its precise cellular function remains elusive. Here we show that PtdIns5P levels increase when cells are stimulated to move and we find PtdIns5P to promote cell migr...

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Detalhes bibliográficos
Main Authors: Oppelt, Angela, Lobert, Viola H, Haglund, Kaisa, Mackey, Ashley M, Rameh, Lucia E, Liestøl, Knut, Oliver Schink, Kay, Marie Pedersen, Nina, Wenzel, Eva M, Haugsten, Ellen M, Brech, Andreas, Erik Rusten, Tor, Stenmark, Harald, Wesche, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537138/
https://ncbi.nlm.nih.gov/pubmed/23154468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.183
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