TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity

Members of the tripartite interaction motif (TRIM) family of E3 ligases are emerging as critical regulators of innate immunity. To identify new regulators, we carried out a screen of 43 human TRIM proteins for the ability to activate NF-κB, AP-1, and interferon, hallmarks of many innate immune signa...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Uchil, Pradeep D., Hinz, Angelika, Siegel, Steven, Coenen-Stass, Anna, Pertel, Thomas, Luban, Jeremy, Mothes, Walther
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536418/
https://ncbi.nlm.nih.gov/pubmed/23077300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01804-12
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky