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TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling
TRIM5 is a restriction factor that blocks retrovirus infection soon after the virion core enters the cell cytoplasm. Restriction activity is targeted to the virion core via recognition of the capsid protein lattice that encases the viral genomic RNA. In common with all of the many TRIM family member...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322363/ https://ncbi.nlm.nih.gov/pubmed/22482711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2012.02.003 |
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