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TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling

TRIM5 is a restriction factor that blocks retrovirus infection soon after the virion core enters the cell cytoplasm. Restriction activity is targeted to the virion core via recognition of the capsid protein lattice that encases the viral genomic RNA. In common with all of the many TRIM family member...

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Detalhes bibliográficos
Main Authors: Grütter, Markus G, Luban, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322363/
https://ncbi.nlm.nih.gov/pubmed/22482711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2012.02.003
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