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TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity

Members of the tripartite interaction motif (TRIM) family of E3 ligases are emerging as critical regulators of innate immunity. To identify new regulators, we carried out a screen of 43 human TRIM proteins for the ability to activate NF-κB, AP-1, and interferon, hallmarks of many innate immune signa...

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Bibliografische gegevens
Hoofdauteurs: Uchil, Pradeep D., Hinz, Angelika, Siegel, Steven, Coenen-Stass, Anna, Pertel, Thomas, Luban, Jeremy, Mothes, Walther
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536418/
https://ncbi.nlm.nih.gov/pubmed/23077300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01804-12
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