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Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice
Autophagy is a vesicular trafficking pathway that regulates the degradation of aggregated proteins and damaged organelles. Initiation of autophagy requires several multiprotein signaling complexes, such as the ULK1 kinase complex and the Vps34 lipid kinase complex, which generates phosphatidylinosit...
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| Autors principals: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536306/ https://ncbi.nlm.nih.gov/pubmed/23109424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01075-12 |
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