Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth

Inherited peripheral neuropathies (IPNs) represent a broad group of disorders including Charcot-Marie-Tooth (CMT) neuropathies characterized by defects primarily arising in myelin, axons, or both. The molecular mechanisms by which mutations in nearly 100 identified IPN/CMT genes lead to neuropathies...

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Publicat a:Nat Commun
Autors principals: Sawade, Linda, Grandi, Federica, Mignanelli, Marianna, Patiño-López, Genaro, Klinkert, Kerstin, Langa-Vives, Francina, Di Guardo, Roberta, Echard, Arnaud, Bolino, Alessandra, Haucke, Volker
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275063/
https://ncbi.nlm.nih.gov/pubmed/32503983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16696-6
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