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First Total Synthesis of Jadomycin A and Carbasugar Analogue of Jadomycin B

The first syntheses of Jadomycin A and the carbosugar analogue of Jadomycin B have been achieved in 6 and 20 longest linear steps respectively. The key ring system of the aglycone was prepared by a 6π-electron electrocyclic ring closure and subsequent hemi-aminal ring closure. Acid sensitivity of th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shan, Mingde, Sharif, Ehesan U., O’Doherty, George A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536065/
https://ncbi.nlm.nih.gov/pubmed/20979078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201005329
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