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HCMV gB shares structural and functional properties with gB proteins from other herpesviruses

Glycoprotein B (gB) facilitates HCMV entry into cells by binding receptors and mediating membrane fusion. The crystal structures of gB ectodomains from HSV-1 and EBV are available, but little is known about the HCMV gB structure. Using multiangle light scattering and electron microscopy, we show her...

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Bibliografiska uppgifter
Huvudupphovsmän: Sharma, Sapna, Wisner, Todd W., Johnson, David C., Heldwein, Ekaterina E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534942/
https://ncbi.nlm.nih.gov/pubmed/23089254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.09.024
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