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Extensive mutagenesis of the HSV-1 gB ectodomain reveals remarkable stability of its postfusion form

Viral fusogens mediate the merger of the viral envelope and cellular membrane during viral entry. These proteins share little sequence similarity but all are thought to act by refolding through a series of conformational intermediates from the metastable prefusion form to the stable postfusion form....

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Detalhes bibliográficos
Main Authors: Vitu, Elvira, Sharma, Sapna, Stampfer, Samuel D., Heldwein, Ekaterina E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655159/
https://ncbi.nlm.nih.gov/pubmed/23500487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.03.001
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