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Extensive mutagenesis of the HSV-1 gB ectodomain reveals remarkable stability of its postfusion form

Viral fusogens mediate the merger of the viral envelope and cellular membrane during viral entry. These proteins share little sequence similarity but all are thought to act by refolding through a series of conformational intermediates from the metastable prefusion form to the stable postfusion form....

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Библиографические подробности
Главные авторы: Vitu, Elvira, Sharma, Sapna, Stampfer, Samuel D., Heldwein, Ekaterina E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655159/
https://ncbi.nlm.nih.gov/pubmed/23500487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.03.001
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