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Human Cytomegalovirus (HCMV) Glycoprotein gB Promotes Virus Entry In Trans Acting as the Viral Fusion Protein Rather than as a Receptor-Binding Protein

Human cytomegalovirus (HCMV) glycoproteins gB and gH/gL are both necessary and sufficient for cell-cell fusion. However, it is not clear what roles these glycoproteins play in virus entry, whether acting directly in membrane fusion or in binding receptors. With other herpesviruses, it appears that g...

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Detalhes bibliográficos
Main Authors: Wille, Paul T., Wisner, Todd W., Ryckman, Brent, Johnson, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685210/
https://ncbi.nlm.nih.gov/pubmed/23736286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00332-13
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