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Glycogen Synthase Kinase 3β and Activin/Nodal Inhibition in Human Embryonic Stem Cells Induces a Pre-Neuroepithelial State That Is Required for Specification to a Floor Plate Cell Lineage

The floor plate is one of the major organizers of the developing nervous system through its secretion of sonic hedgehog (Shh). Although the floor plate is located within the neural tube, the derivation of the floor plate during development is still debatable and some studies suggest that floor plate...

Szczegółowa specyfikacja

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Opis bibliograficzny
Główni autorzy: Denham, Mark, Bye, Chris, Leung, Jessie, Conley, Brock J, Thompson, Lachlan H, Dottori, Mirella
Format: Artigo
Język:Inglês
Wydane: Wiley Subscription Services, Inc., A Wiley Company 2012
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533765/
https://ncbi.nlm.nih.gov/pubmed/22911885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1204
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