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Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
Knockout mouse models targeting various cytochrome P450 (P450 or CYP) genes are valuable for determining P450’s biologic functions, including roles in drug metabolism and chemical toxicity. In this study, a novel Cyp2a(4/5)bgs-null mouse model was generated, in which a 1.2-megabase pair genomic frag...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533424/ https://ncbi.nlm.nih.gov/pubmed/23073733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.048736 |
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