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Impact of Nicotine Metabolism on Nicotine’s Pharmacological Effects and Behavioral Responses: Insights from a Cyp2a(4/5)bgs-Null Mouse
Nicotine metabolism is believed to affect not only nicotine’s pharmacological effects but also nicotine addiction. As a key step toward testing this hypothesis, we have studied nicotine metabolism and nicotine’s pharmacological and behavioral effects in a novel knockout mouse model [named Cyp2a(4/5)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836308/ https://ncbi.nlm.nih.gov/pubmed/24045421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208256 |
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