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Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model

CYP2A13, CYP2B6, and CYP2F1 are neighboring cytochrome P450 genes on human chromosome 19, and the enzymes that they encode overlap in substrate specificity. A CYP2A13/2B6/2F1-transgenic mouse, in which CYP2A13 and 2F1 are both expressed in the respiratory tract and CYP2B6 is expressed in the liver,...

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Detalhes bibliográficos
Main Authors: Jia, Kunzhi, Li, Lei, Liu, Zhihua, Hartog, Matthew, Kluetzman, Kerri, Zhang, Qing-Yu, Ding, Xinxin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109209/
https://ncbi.nlm.nih.gov/pubmed/24907355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.059188
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