Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model

CYP2A13, CYP2B6, and CYP2F1, which are encoded by neighboring cytochrome P450 genes on human chromosome 19, are active in the metabolic activation of many drugs, respiratory toxicants, and chemical carcinogens. To facilitate studies on the regulation and function of these human genes, we have genera...

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Detalhes bibliográficos
Main Authors: Wei, Yuan, Wu, Hong, Li, Lei, Liu, Zhihua, Zhou, Xin, Zhang, Qing-Yu, Weng, Yan, D'Agostino, Jaime, Ling, Guoyu, Zhang, Xiuling, Kluetzman, Kerri, Yao, Yunyi, Ding, Xinxin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362791/
https://ncbi.nlm.nih.gov/pubmed/22397853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.044826
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