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Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model

CYP2A13, CYP2B6, and CYP2F1, which are encoded by neighboring cytochrome P450 genes on human chromosome 19, are active in the metabolic activation of many drugs, respiratory toxicants, and chemical carcinogens. To facilitate studies on the regulation and function of these human genes, we have genera...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wei, Yuan, Wu, Hong, Li, Lei, Liu, Zhihua, Zhou, Xin, Zhang, Qing-Yu, Weng, Yan, D'Agostino, Jaime, Ling, Guoyu, Zhang, Xiuling, Kluetzman, Kerri, Yao, Yunyi, Ding, Xinxin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Pharmacology and Experimental Therapeutics 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362791/
https://ncbi.nlm.nih.gov/pubmed/22397853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.044826
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