Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

Nephrocalcinosis, acute calcium oxalate (CaOx) nephropathy, and renal stone disease can lead to inflammation and subsequent renal failure, but the underlying pathological mechanisms remain elusive. Other crystallopathies, such as gout, atherosclerosis, and asbestosis, trigger inflammation and tissue...

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Bibliografische gegevens
Hoofdauteurs: Mulay, Shrikant R., Kulkarni, Onkar P., Rupanagudi, Khader V., Migliorini, Adriana, Darisipudi, Murthy N., Vilaysane, Akosua, Muruve, Daniel, Shi, Yan, Munro, Fay, Liapis, Helen, Anders, Hans-Joachim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533282/
https://ncbi.nlm.nih.gov/pubmed/23221343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63679
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