Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

Nephrocalcinosis, acute calcium oxalate (CaOx) nephropathy, and renal stone disease can lead to inflammation and subsequent renal failure, but the underlying pathological mechanisms remain elusive. Other crystallopathies, such as gout, atherosclerosis, and asbestosis, trigger inflammation and tissue...

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Detalhes bibliográficos
Main Authors: Mulay, Shrikant R., Kulkarni, Onkar P., Rupanagudi, Khader V., Migliorini, Adriana, Darisipudi, Murthy N., Vilaysane, Akosua, Muruve, Daniel, Shi, Yan, Munro, Fay, Liapis, Helen, Anders, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533282/
https://ncbi.nlm.nih.gov/pubmed/23221343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63679
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